SAPHO syndrome

Epidemiology

Clinical findings

Synovitis, acne, pustulosis, hyperostosis, osteiitis

Cutaneous 84%

Hidradenitis supurativa

HLA-B27 positive in Japan low amount. 13-18% France. 4% Italy.

Is SAPHO an autoinflammatory syndrome?

PAPA syndrome. PSTPIP1 gene. Pyrin binding disease. [1]

Treatment