Urinary tract infection (UTI)

Urinary infection is commonly encountered in a medical practice. Most cases are what are called simple UTI probably in the bladder also called cystitis or uncomplicated cystitis.

UTI in the elderly

Many elderly people have bacteruria, bacteria in the urine that is not causing infection. 

Treatment

Non-pharmacological treatment

Physical therapy

Pharmacological treatment

Ciprofloxacin (Cipro)

Cystitis, acute uncomplicated or acute simple cystitis (infection limited to the bladder without signs/symptoms of upper tract, prostate, or systemic infection) (alternative agent):


Note: Use is discouraged due to safety concerns and increasing resistance; reserve for those who have no alternative treatment options. However, for men who have severe symptoms or there is concern for early prostate involvement, some experts prefer fluoroquinolones.


Oral: Immediate release: 250 mg every 12 hours; for treatment of resistant gram-negative infection (eg, extended-spectrum beta-lactamase [ESBL]-producing Enterobacterales, AmpC beta-lactamase-producing Enterobacterales), some experts recommend 500 mg every 12 hours.


Duration: 3 days (females) or 5 days (males)


Renal dosing

CrClOral, IR

50-130500-750 q 12 hrs

30-50250-500 q 12 hrs

<30500 mg. q 24 hrs

HD


PD



[1]Ciprofloxacin (systemic): Drug information. Uptodate